Parameter | Test statistic (H) | ε2 [95% CI] | P-value | Adj. P-value | Healthy | miEA | modEA | sEA |
|---|
Nasal Discharge Score | 13.2 | 0.53 [0.35–1] | 0.004 | 0.017 | a | ab | ab | b |
Cough Score | 23.1 | 0.93 [0.88–1] | 0 | 0 | a | ab | bc | c |
Dyspnoea Score | 15.8 | 0.63 [0.51–1] | 0.001 | 0.007 | a | a | ab | b |
Auscultation Score | 19.6 | 0.79 [0.74–1] | 0 | 0.001 | a | a | ab | b |
Clinical Score | 21 | 0.84 [0.8–1] | 0 | 0.001 | a | ab | bc | c |
Secretion Score | 13.8 | 0.55 [0.44–1] | 0.003 | 0.016 | a | ab | ab | b |
Viscosity Score | 12.2 | 0.49 [0.38–1] | 0.007 | 0.02 | a | a | ab | b |
Swelling Score | 2.18 | 0.09 [0.04–1] | 0.535 | 0.535 | – | – | – | – |
Endoscopy Score | 11.8 | 0.47 [0.4–1] | 0.008 | 0.02 | a | ab | ab | b |
- Overview of score comparisons between diagnoses using Kruskal–Wallis tests. The results indicate that the clinical use of the presented subscores is limited due to overlapping scores among phenotypes. The Kruskal–Wallis test statistics (H) and the effect sizes epsilon squared (ε2) are presented, alongside the latter’s 95% confidence intervals. All scores but the swelling score show significant differences between the groups (adj. P-values ≤ 0.05), which indicates overall large variations between healthy and diseased animals. Different letters in the ‘healthy’, ‘miEA’, ‘modEA’ and ‘sEA’ indicate significant differences between those groups in Dunn’s post-hoc comparisons. For example, the endoscopy score significantly differs between the healthy and sEA group (letters a vs. b), but neither miEA nor modEA are significantly different from the other groups, as they share the letters a, b, or both. It follows that the significant results from the Kruskal–Wallis tests are mainly attributable to the sEA group, which shows the most marked differences compared to the remaining phenotypes. All horses were included in the analysis (n = 26). The P-values from the Kruskal–Wallis tests were adjusted for multiple comparisons with the Holm procedure. (Abbr.: Adj. P-value = adjusted P-value, miEA = mild equine asthma, modEA = moderate equine asthma, sEA = severe equine asthma)
