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Table 3 Histopathological features of mast cell tumors in dogs

From: Histopathological features of subcutaneous and cutaneous mast cell tumors in dogs

Variables

ScMCTs

cMCTs

Total

P-value

N

%

N

%

N

%

 

Bizarre nuclei and multinucleation

283

100

1272

100

1555

100

< 0.0001

 None or 1/10 HPF

247

87.3

1188

93.4

1435

92.3

 

 Yes, less than 3/10 HPF

0

0.0

10

0.8

10

0.6

 

 Yes, more than 3/10 HPF

1

0.4

60

4.7

61

3.9

 

 Yes, unspecified

35

12.4

14

1.1

49

3.2

 

Eosinophil number

289

100

1269

100

1558

100

< 0.0001

 High

89

30.8

218

17.2

307

19.7

 

 Moderate

61

21.1

520

41.0

581

37.3

 

 Low

139

48.1

531

41.8

670

43.0

 

Anisokaryosisa

188

100

811

100

999

100

= 0.0269

 Less than 5%

163

86.7

735

90.6

898

89.9

 

 Between 5–10%

0

0

0

0

0

0

 

 More than 10%

25

13.3

76

9.4

101

10.1

 
  1. Histopathological features of canine subcutaneous mast cell tumors (scMCTs), cutaneous mast cell tumors (cMCTs) and of the total group of mast cell tumors, displayed in absolute number (N) and relative percentage (%). Significant differences were observed between scMCTs and cMCTs
  2. aAs % of neoplastic cells of the total neoplastic cell population, that exhibits a 2-fold variation in nuclear size (pathologist A)